Welcome to Winston-Salem – where Southern charm shakes hands with artsy vibes and the smell of fresh coffee mingles with historic tobacco heritage.
This North Carolina gem offers everything from world-class museums to lush greenways, but let’s be real – you’ll need an equally awesome place to rest your head after all that exploring.
We’ve scoured every corner of the Twin City to bring you the absolute best hotels in Winston-Salem, whether you’re here for Wake Forest parents’ weekend, a romantic getaway, or just passing through on your Carolina road trip.
From historic downtown charmers to modern stays with all the perks, we’ve got your perfect home base covered. Ready to find your match?
1. The Historic Brookstown Inn – Best Overall
Step back in time at this 1840s cotton mill turned boutique hotel – the Historic Brookstown Inn is hands-down Winston-Salem’s most unique stay.
Exposed brick walls, original wooden beams, and antique furnishings give this place character you won’t find at chain hotels.
Their evening wine-and-cheese receptions (with non-alcoholic options) and fresh-baked cookies at night make you feel like family.
Rooms blend historic charm with modern comforts – think plush beds, free WiFi, and rainfall showers. The complimentary continental breakfast featuring local pastries is the perfect start to your day.
Located in the historic West End district, you’re just a short walk from Old Salem Museums & Gardens and downtown’s best restaurants. For a one-of-a-kind Winston-Salem experience, this is our top pick.
2. Hampton Inn & Suites Winston-Salem Downtown – Best Budget-Friendly
Who says downtown stays have to break the bank? The Hampton Inn & Suites delivers prime location and comfort at wallet-friendly prices.
Their free hot breakfast with made-to-order omelets will save you both time and money each morning.
The indoor pool is perfect for unwinding, while the fitness center helps you stay on track.
Rooms are clean and contemporary with fridge/microwave combos – great for leftovers from nearby gems like Sweet Potatoes Restaurant.
Just two blocks from Benton Convention Center, it’s ideal for both business and leisure travelers wanting affordable downtown access.
3. Kimpton Cardinal Hotel – Best for Luxury Lovers
Housed in the 1929 R.J. Reynolds Building, the Kimpton Cardinal Hotel is Winston-Salem’s crown jewel of luxury.
The stunning Art Deco lobby with its original marble floors and brass details will make you feel like you’ve stepped onto a movie set.
Rooms blend historic architecture with bold, modern design – think floor-to-ceiling windows and custom artwork.
Their 24-hour fitness center and complimentary bike rentals help you explore in style. Don’t miss their evening social hour where you can mingle with other guests.
Located right on Fourth Street (Winston’s dining and entertainment hub), you’re steps from theaters, galleries, and chef-driven restaurants. For a splurge-worthy stay, the Cardinal delivers.
4. Fairfield Inn & Suites Winston-Salem – Best for Families
Traveling with kids? The Fairfield Inn & Suites gets family travel right. Their spacious suites with sofa beds give everyone room to spread out, and the indoor pool is a lifesaver on rainy days.
The free breakfast buffet has something for even picky eaters, and the free WiFi keeps teens happy.
Located near Tanglewood Park (with its legendary holiday lights display), you’ll have family-friendly activities right at your doorstep.
Parents will appreciate the on-site laundry and quick highway access when it’s time to explore beyond Winston.
5. Marriott Winston-Salem – Best for Business Travelers
Need to mix work and comfort? The Marriott Winston-Salem nails it with ergonomic workstations in every room and a 24/7 business center.
Their M Club Lounge (for elite members) offers quiet workspace and complimentary refreshments.
The on-site restaurant serves up reliable American fare when you’re too busy to go out, and the indoor pool helps you unwind after meetings.
Located right next to Benton Convention Center, it’s a no-brainer for conference attendees.
With 10,000 square feet of meeting space, it’s equally great for hosting your own corporate events.
6. The Shaffner Inn – Best for Romantic Getaways
Looking to spark some magic? The Shaffner Inn, a beautifully restored 1909 mansion, is Winston-Salem’s most romantic hideaway.
Each of the eight guest rooms has its own personality – we’re talking four-poster beds, clawfoot tubs, and private balconies perfect for morning coffee together.
Their three-course gourmet breakfast (included with your stay) features seasonal local ingredients and is served on fine china in the sunlit dining room.
The wrap-around porch with its rocking chairs is prime real estate for evening conversations, and the honor bar in the parlor keeps the good vibes flowing.
Tucked in the historic West End neighborhood, you’re just a short stroll from Reynolda Village’s charming shops and downtown’s intimate restaurants.
For couples who want old-world charm with modern comforts, this B&B is pure romance.
7. Holiday Inn Express Winston-Salem – Best for Road Trippers
Cruising along I-40? The Holiday Inn Express offers easy on/off access without the highway noise.
Their signature cinnamon rolls at the free breakfast are legendary – worth setting your alarm a little earlier.
The outdoor pool is refreshing after hours behind the wheel, and rooms with blackout curtains ensure you’ll actually get rest. Pet-friendly options mean your four-legged copilot can join the adventure too.
What really sets it apart? The 24-hour business center with free printing – a lifesaver when you need to check maps or print tickets. For travelers who want comfort without detours, this hotel is a no-brainer.
8. Courtyard by Marriott Winston-Salem Hanes Mall – Best for Modern Comfort
The Courtyard by Marriott nails that sweet spot between business-ready and relaxation-friendly.
Their refreshed lobby concept features flexible workspaces and a Starbucks® counter for that essential morning jolt.
Rooms boast plush Marriott bedding and ergonomic workstations. The Bistro restaurant serves up hearty American fare when you don’t feel like going out.
The indoor pool is a rare find in Winston hotels – perfect for year-round use.
Located near Hanes Mall and Wake Forest Innovation Quarter, it’s equally convenient for shoppers and business travelers. The free airport shuttle to Smith Reynolds is the cherry on top.
9. Home2 Suites by Hilton Winston-Salem – Best for Extended Stays
Planning to stick around awhile? Home2 Suites delivers apartment-style living with hotel perks.
Their full kitchens (complete with dishwashers!) and separate living areas make long stays comfortable.
The complimentary breakfast goes beyond basics with customizable options. The outdoor patio with grills is perfect for summer cookouts.
Located near Wake Forest Baptist Medical Center, it’s popular with travel nurses and relocating families.
For space to spread out without sacrificing amenities, this all-suite hotel is a game-changer.
10. Best Western Plus University Inn – Best for Wake Forest Visits
If you’re in town for college visits or Demon Deacon games, this Best Western Plus puts you minutes from campus.
Their expanded continental breakfast includes hot items like scrambled eggs and sausage.
The indoor pool is nice when you need to relax between campus tours. Rooms feature microwaves and mini-fridges – crucial for late-night snacks after games.
Their free parking (a rarity near campus) and business center make it practical for visiting families. For stress-free university visits, this location can’t be beat.
11. Hyatt Place Winston-Salem – Best for Flexible Travelers
The Hyatt Place Winston-Salem gets high marks for adaptability. Their open-concept rooms with partition walls give you separate living and sleeping areas without feeling cramped.
The 24/7 Gallery Menu means you can eat what you want, when you want (the signature flatbreads are killer). The outdoor pool has plenty of lounge space for sunbathing.
Located near Wake Forest Innovation Quarter and Bailey Park, it works equally well for work and play. The free shuttle service within a 5-mile radius is perfect for dinner outings.
12. Sonesta Simply Suites Winston-Salem – Best for No-Frills Comfort
Sometimes you just need a clean, comfortable place to crash without bells and whistles. Sonesta Simply Suites delivers essential comforts at wallet-friendly rates.
The studio suites with kitchenettes give you flexibility for longer stays. While amenities are basic, you get free WiFi and pet-friendly policies. The on-site guest laundry is a practical perk.
Near Hanes Mall and Tanglewood Park, it’s perfect for travelers who prioritize location over luxury. Sometimes simple is exactly what you need.
Final Thoughts
From historic gems to modern retreats, Winston-Salem’s hotel scene offers something for every traveler.
Whether you’re here to explore Moravian heritage, cheer on the Demon Deacons, or discover the city’s growing arts scene, your perfect home base awaits.
Don’t just visit Winston-Salem – experience it in comfort and style. Which of these amazing hotels speaks to your travel needs? Book your favorite today and get ready to fall in love with this North Carolina treasure!