Port St. Lucie, Florida, is a hidden gem on the Treasure Coast, offering stunning beaches, lush golf courses, and a laid-back vibe that’s perfect for a relaxing getaway.
Whether you’re here for a family vacation, a romantic escape, or a solo adventure, picking the right hotel can make or break your trip.
Lucky for you, we’ve scoured the city to bring you the absolute best hotels in Port St. Lucie—each with its own unique charm.
From luxury resorts to budget-friendly stays, we’ve got something for every traveler. Ready to find your perfect home away from home? Let’s dive in!
1. Home2 Suites by Hilton Port St. Lucie – Best Overall
If you’re looking for a top-tier stay that balances comfort, convenience, and value, Home2 Suites by Hilton is your best bet.
This all-suite hotel offers spacious rooms with full kitchens, making it ideal for extended stays or families who want a little extra room.
The modern, eco-friendly design gives it a fresh, welcoming vibe. Plus, the free breakfast is a game-changer, with plenty of options to fuel your day.
Love staying active? They’ve got an outdoor pool and fitness center, so you can keep up with your routine.
And with its prime location near shopping and dining, you’re never far from the action.
For a hassle-free, high-quality stay, Home2 Suites is the best overall pick in Port St. Lucie.
2. Holiday Inn Express & Suites Port St. Lucie-West – Best Budget-Friendly
Traveling on a budget doesn’t mean you have to skimp on comfort. The Holiday Inn Express & Suites delivers great value without cutting corners.
The rooms are clean, cozy, and equipped with all the essentials—think comfy beds, flat-screen TVs, and free Wi-Fi. The complimentary breakfast is a crowd-pleaser, featuring their famous cinnamon rolls.
Located just off I-95, it’s a convenient base for exploring Port St. Lucie’s attractions. Whether you’re here for business or leisure, this hotel keeps things simple and affordable.
If you want a solid stay without breaking the bank, this is your spot.
3. Residence Inn by Marriott Port St. Lucie – Best for Families
Traveling with kids? The Residence Inn by Marriott is a family favorite for good reason.
The suite-style rooms give everyone space to spread out, and the full kitchens mean you can whip up meals instead of eating out every night.
Kids will love the outdoor pool, while parents appreciate the free grocery delivery service. The hotel also offers a social hour with light bites, making it easy to unwind after a busy day.
With its home-like feel and family-friendly perks, this hotel makes vacations smoother (and way more fun) for everyone.
4. Hampton Inn & Suites Port St. Lucie – Best for Business Travelers
Need a productive stay? The Hampton Inn & Suites has everything a business traveler needs. Fast Wi-Fi, a 24/7 business center, and comfortable workspaces in every room keep you on top of your game.
The free hot breakfast is a major perk, and the fitness center helps you stay energized. Plus, its location near major highways makes commuting a breeze.
For a no-nonsense, efficient stay, this Hampton Inn has you covered.
5. Fairfield Inn & Suites by Marriott Port St. Lucie – Best for Couples
Romantic getaway? The Fairfield Inn & Suites offers a quiet, intimate vibe perfect for couples. The sleek, modern rooms provide a cozy retreat, and the outdoor pool is ideal for lazy afternoons together.
Located near scenic parks and beaches, it’s a great base for sunset strolls and romantic dinners. Plus, the free breakfast means you can start your day stress-free.
For a relaxing couples’ escape, this hotel hits all the right notes.
6. SpringHill Suites by Marriott Port St. Lucie – Best for Extended Stays
If you’re planning a longer visit to Port St. Lucie, SpringHill Suites by Marriott is the ultimate home-away-from-home.
Their spacious studio suites feature separate living and sleeping areas, mini-fridges, and microwaves—perfect for travelers who want extra comfort.
The free breakfast buffet is a real winner, with hot and cold options to please every palate. And when it’s time to unwind, the outdoor pool and 24-hour fitness center have you covered.
Located near top attractions like the Port St. Lucie Botanical Gardens and Savannas Preserve State Park, this hotel makes it easy to explore. For a stress-free extended stay, SpringHill Suites delivers.
7. Tru by Hilton Port St. Lucie – Best for Millennials & Young Travelers
Vibrant, modern, and packed with personality—Tru by Hilton is the go-to spot for young travelers who want a fun, social atmosphere.
The colorful, tech-savvy rooms feature oversized windows, Bluetooth mirrors, and plenty of USB ports.
The communal lobby is where the magic happens, with games, a 24/7 market, and free coffee. There’s even a “Build Your Own” breakfast bar, so you can fuel up your way.
If you love budget-friendly stays with a trendy twist, Tru by Hilton is your jam.
8. Comfort Suites Port St. Lucie – Best for Spacious Comfort
Need extra room to stretch out? Comfort Suites offers suite-style accommodations with separate living areas, making it a fantastic choice for families or groups.
The indoor pool is a rare perk in Florida’s heat, and the free hot breakfast ensures a strong start to your day.
Plus, its central location puts you minutes from shopping, dining, and outdoor adventures.
For big rooms at a reasonable price, Comfort Suites is a standout pick.
9. Holiday Inn Port St. Lucie – Best for Golf Lovers
Calling all golfers! The Holiday Inn Port St. Lucie sits right next to the PGA Village, making it a dream stay for golf enthusiasts.
After a day on the greens, relax in their outdoor pool or grab a bite at the on-site restaurant.
Rooms are clean, comfy, and designed for relaxation. And with easy access to I-95, you’re well-connected to the best of the Treasure Coast.
If golf is your game, this hotel is your perfect 19th hole.
10. Quality Inn & Suites Port St. Lucie – Best for Road Trippers
If you’re cruising down Florida’s coast, the Quality Inn & Suites is a smart pit stop. Right off Highway 95, it offers affordable rates, clean rooms, and a free breakfast to get you back on the road fast.
The outdoor pool is great for a quick dip, and pets are welcome (with a small fee), so your furry friend can join the adventure.
For no-frills comfort on a road trip, this hotel hits the mark.
11. Best Western Plus Port St. Lucie – Best for Business & Leisure Mix
Can’t decide between work and play? The Best Western Plus blends both seamlessly.
Their business center and meeting spaces cater to professionals, while the heated pool and free breakfast add a vacation vibe.
Rooms are sleek and modern, with ergonomic workspaces and plush bedding. And with downtown Port St. Lucie just minutes away, you’ll have plenty to explore.
For a perfect work-play balance, this hotel nails it.
12. Suburban Studios Port St. Lucie – Best for Budget Long-Term Stays
Need an affordable extended stay? Suburban Studios offers simple, no-nonsense suites with kitchenettes, making it ideal for travelers on a budget.
While it’s no-frills, you still get free Wi-Fi, on-site laundry, and easy highway access. It’s a practical choice for contractors, relocators, or anyone needing a longer stay without the high cost.
For cheap and cheerful lodging, Suburban Studios gets the job done.
Final Thoughts
Port St. Lucie is packed with amazing hotels for every type of traveler. Whether you want luxury, affordability, or family-friendly fun, there’s a perfect stay waiting for you.
So what are you waiting for? Pick your favorite, pack your bags, and get ready for an unforgettable Florida getaway!
Which hotel caught your eye? Book now before the best rooms get snapped up!